I am a huge skeptic when it comes to the claims of skin care companies, having shelled out precious $$$ for promises that rarely came true, but I saw Skinceuticals products in the dermatologist's office a few weeks ago and decided to try the Retinol 1.0 Refining Night Cream. I used it twice last week, and today I noticed that brown spots I have been plagued with for the past few years are now nearly invisible. Am recommending this product to all my friends!